Research Projects

UTHealth— Double-Blind, Randomized Placebo-Controlled Study of CM-AT for the Treatment of Autism in Children

14-week study to evaluate the safety and effectiveness of an investigational medication designed to treat the symptoms of autism in children.

Subject must be: 3-8 years of age and have a diagnosis of ASD

Subject may be ineligible: if they weigh less than 28lbs; have an allergy to pork products and/or pancreatic enzymes; has a history of seizures; has a history of severe head trauma and/or stroke; is diagnosed with a chronic illness

Participants will receive study medication and screening evaluation at no cost. They will also receive compensation for parking, and monetary compensation for their time and efforts.

To be screened, or to obtain further information, please contact Rosleen Mansour at (713) 486-2591.

University of Houston- Autism Spectrum Disorder Research Study

WHAT WE ARE STUDYING
• Parent-child interactions of families of children with ASD
• Differences between mother and father behaviors during play interactions
WHO WE NEED
• Children with a diagnosis of ASD or special education eligibility of autism (AU), ages 2-12
• Mothers and fathers of children with ASD
STUDY DETAILS
• Total time commitment: 1.5 hours
• Parents will complete a demographic questionnaire, two parent rating scales, and engage in two 5-
minute play interactions with their child
• Child's receptive language level will be assessed and each child will engage in two 5-minute play
interactions with each parent
REWARD
• Opportunity to receive up to three $50 Target gift cards
• Verbal feedback regarding your play interactions with your child
• List of strategies to help promote positive play interactions with your child
IF INTERESTED
• Contact Rachel Halpern Fein, M.Ed., BCBA by email at rachelhalpernfein@gmail.com .

This project has been reviewed by the University of Houston Committee for the Protection of Human Subjects
(713) 743.9204.

Stanford University Autism Research Studies

WEBSITE

Study to Explore Early Development (SEED)

The Study to Explore Early Development (SEED) is a multi-year study funded by CDC. It is currently the largest study in the United States to help identify factors that may put children at risk for autism spectrum disorders (ASDs) and other developmental disabilities. Understanding the risk factors that make a person more likely to develop an ASD will help us learn more about the causes. The study will include children with ASD, developmental disabilities and those with typical development, ages 2-5 years.

The study is being conducted in the following states: California, Colorado, Georgia, Maryland, North Carolina, and Pennsylvania. For more information visit:

WEBSITE

Severe Behavior Disorders Research Clinic at University of Houston-Clear Lake

This clinic offers assessment and treatment services to children of all ages who engage in severe problem behavior, such as self-injurious behavior, aggression, and property destruction. Services will be individualized and provided as part of ongoing studies designed to identify the most effective methods of reducing severe behavior disorders. Following the child's participation in research, families will receive training in effective behavior management strategies to use at home.
For more information, contact Dr. Jennifer Fritz at behaviorclinic@uhcl.edu
Visit the website for more information about the 2011-2012 program:

behaviorclinic@uhcl.edu
WEBSITE

Project REDD, with Texas A&M University

(979) 845-8257, lstough@tamu.edu
WEBSITE

Treatment of Sleep Problems in Children With Autism Spectrum Disorder With Melatonin: A Double-blind, Placebo-controlled Study

Patients are needed to participate in a clinical research study of Melatonin and Placebo to evaluate Sleep Problems.

The investigators will examine whether sleep problems in children with autism spectrum disorder (ASD) are related to alterations in the production of melatonin (MT), a hormone that plays an important role in regulating sleep-wake cycle. Furthermore, the investigators will examine whether MT is effective in improving sleep in children with ASD. Children with ASD experience high rates of sleep disturbances that potentially contribute to problems with thinking and behavior. It is unclear if changes in MT production cause sleep problems in children with ASD. MT is frequently used to treat these sleep problems; however, it has not been well established whether MT is an effective treatment. Our hypotheses concerning MT are: 1. Children with ASD and sleep problems will have a delayed sleep-wake cycle and/or decreased MT production; 2. Treatment with MT will be associated with improved sleep and behavior. All subjects will be recruited from one of three sites: Baylor College of Medicine, Oregon Health & Science University and Columbia University. The investigators will use a standardized questionnaire to determine whether the child has sleep problems. The investigators will measure MT levels in saliva in ASD children with sleep problems and in a group of ASD children without sleep problems. Total 24-hour MT production will be determined from urine samples in these same two groups. Eligible participants will then be enrolled in a randomized trial of three oral doses of MT (3, 6, 9 mg) and a placebo. Neither children nor investigators will know which doses are being given to which participants. The investigators will determine whether treatment with MT helps children fall asleep faster and whether their behavior improves, as reported on standardized questionnaires. Results from this study will inform the development of future trials of sleep-wake interventions and clinical guidelines for the use of MT to manage sleep problems in ASD.
Baylor College of Medicine

Bobbi Hopkins, M.D.
832-822-1764
bhopkins@bcm.tmc.edu

Daniel G Glaze, M.D.
Sub-Investigator

Bobbi Hopkins
Principal Investigator

Enhancing Early Learning for Infants with Special Needs

A research study that investigates programs for parents that focus on enhancing learning in children with special needs. Participants in the study will be assigned to one of three different groups that target motor learning, social functioning, and language development.

The program aims to help parents enhance their child's learning by providing information and resources pertaining to child development, and education materials. Some groups will receive access to trained coaches who will guide parents in responsive and motor learning behaviors that may benefit children with special needs.

Jose Vega

713-500-3712

Jese.vega@uth.tmc.edu

Heather B. Taylor, Ph.D.

Principal Investigator

Texas Women's University: Seeking Parents of Children with Autism and ADHD

Researching how parent's cultural perceptions influence their willingness to accept a diagnoses and psychological services/treatments for children with Autism and ADHD.

The survey requires one-time participation at the website.

For more information, email:

mdenis@twu.edu

kdeornellas@twu.edu

Cross-Cultural Study in Mothers of Children with Autism

Seeking mothers of children with Autism who are aged 2-12 years.

This research study will compare mothers' experience of raising children with Autism between Japan and the U.S.A. You will be asked to fill out a questionaiire (60 minutes) and be interviewed (30 minutes). All participants will recieve a gift card as compensation for their participation.

For more information:

Noriko Porter

noriko.porter@uth.tmc.edu

Survey About Siblings of Individuals with Disabilities, their Support needsand their Families

The purpose of this research is to identify needed supports for siblings of individuals with disabilities. The survey will include questions about yourself, your concerns, and your experiences as one of the following:

-a sibling of a person with a disability

-a person with a disability

-a parent of a person with a disability

-a professional who works with people with disabilities and/or their families

We live in a world in which we need to share responsibility. It’s easy to say “It’s not my child, not my community, not my world, not my problem. “Then there are those who see the need and respond. I consider those people my heroes”
Fred Rogers